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1. Zhou Y & Bowie JU. (2000). J Biol Chem 275, 6975-6979. Building a thermostable membrane protein.

2. Lau FW, Nauli S, Zhou Y & Bowie JU. (1999). J Mol Biol 290, 559-564. Changing single side-chains can greatly enhance the resistance of a membrane protein to irreversible inactivation.

3. Bowie JU. (2000). Curr. Op. Str. Biol. 10, 435-437.

4. Russell RB & Eggleston DS. (2000). Nat Struct Biol 7 Suppl, 928-930. New roles for structure in biology and drug discovery.

5. http://www.mpibp-frankfurt.mpg.de/michel/public/memprotstruct.html. Membrane proteins of Known Structure.

6. Chen GQ & Gouaux E. (1997). Protein Eng 10, 1061-1066. Reduction of membrane protein hydrophobicity by site-directed mutagenesis: introduction of multiple polar residues in helix D of bacteriorhodopsin.

7. Wells JA. (1990). Biochemistry 29, 8509-8517. Additivity of mutational effects in proteins.

8. Skinner MM & Terwilliger TC. (1996). Proc Natl Acad Sci U S A 93, 10753-10757. Potential use of additivity of mutational effects in simplifying protein engineering.

9. Hendrickson WA. (1991). Science 254, 51-58. Determination of macromolecular structures from anomalous diffraction of synchrotron radiation.

10. Egea PF, Shan SO, Napetschnig J, Savage DF, Walter P & Stroud RM. (2004). Nature 427, 215-221. Substrate twinning activates the signal recognition particle and its receptor.

11. Abramson J, Smirnova I, Kasho V, Verner G, Iwata S & Kaback HR. (2003). FEBS Lett 555, 96-101. The lactose permease of Escherichia coli: overall structure, the sugar-binding site and the alternating access model for transport.

12. Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR & Iwata S. (2003). Science 301, 610-615. Structure and mechanism of the lactose permease of Escherichia coli.

13. Tate CG, Kunji ER, Lebendiker M & Schuldiner S. (2001). Embo J 20, 77-81. The projection structure of EmrE, a proton-linked multidrug transporter from Escherichia coli, at 7 A resolution.

14. Stahlberg H, Engel A & Philippsen A. (2002). Biochem Cell Biol 80, 563-568. Assessing the structure of membrane proteins: combining different methods gives the full picture.

15. Stahlberg H, Braun T, de Groot B, Philippsen A, Borgnia MJ, et al. (2000). J Struct Biol 132, 133-141. The 6.9-A structure of GlpF: a basis for homology modeling of the glycerol channel from Escherichia coli.

16. Luecke H, Schobert B, Cartailler JP, Richter HT, Rosengarth A, et al. (2000). J Mol Biol 300, 1237-1255. Coupling photoisomerization of retinal to directional transport in bacteriorhodopsin.

17. Luecke H, Schobert B, Lanyi JK, Spudich EN & Spudich JL. (2001). Science 293, 1499-1503. Crystal structure of sensory rhodopsin II at 2.4 angstroms: insights into color tuning and transducer interaction.

18. Lanyi JK & Luecke H. (2001). Curr Opin Struct Biol 11, 415-419. Bacteriorhodopsin.

19. Luecke H, Schobert B, Richter HT, Cartailler JP & Lanyi JK. (1999). J Mol Biol 291, 899-911. Structure of bacteriorhodopsin at 1.55 A resolution.

20. Palczewski K, Kumasaka T, Hori T, Behnke CA, Motoshima H, et al. (2000). Science 289, 739-745. Crystal structure of rhodopsin: A G protein-coupled receptor.

21. Heymann JB & Engel A. (2000). J Mol Biol 295, 1039-1053. Structural clues in the sequences of the aquaporins.

22. Stroud RM & Walter P. (1999). Curr Opin Struct Biol 9, 754-759. Signal sequence recognition and protein targeting.

23. Keenan RJ, Freymann DM, Stroud RM & Walter P. (2001). Annu Rev Biochem 70, 755-775. The signal recognition particle.

24. Andersson H, D'Antona AM, Kendall DA, Von Heijne G & Chin CN. (2003). Mol Pharmacol 64, 570-577. Membrane assembly of the cannabinoid receptor 1: impact of a long N-terminal tail.

25. Weiss HM & Grisshammer R. (2002). Eur J Biochem 269, 82-92. Purification and characterization of the human adenosine A(2a) receptor functionally expressed in Escherichia coli.

26. Calandra B, Tucker J, Shire D & Grisshammer R. (1997). Biotechnology Letters 19, 425-. Expression in E.coli and characterization of the human central CB1 and peripheral CB2 cannabinoid receptors.

27. Grisshammer R & Tucker J. 2000. G Protein - Coupled Receptors. 265-280.

28. Miroux B & Walker JE. (1996). J Mol Biol 260, 289-298. Over-production of proteins in Escherichia coli: mutant hosts that allow synthesis of some membrane proteins and globular proteins at high levels.

29. Arechaga I, Miroux B, Karrasch S, Huijbregts R, de Kruijff B, et al. (2000). FEBS Lett 482, 215-219. Characterisation of new intracellular membranes in Escherichia coli accompanying large scale over-production of the b subunit of F(1)F(o) ATP synthase.

30. Reimer RJ, Fremeau RT, Jr., Bellocchio EE & Edwards RH. (2001). Curr Opin Cell Biol 13, 417-421. The essence of excitation.

31. Ni B, Rosteck PR, Jr., Nadi NS & Paul SM. (1994). Proc Natl Acad Sci U S A 91, 5607-5611. Cloning and expression of a cDNA encoding a brain-specific Na(+)-dependent inorganic phosphate cotransporter.

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