Earl Wilbur Sutherland, Jr.
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| Earl Wilbur Sutherland, Jr. | |
 Earl Wilbur Sutherland, Jr.
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| Born | November 19, 1915 Burlingame, Kansas |
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| Died | March 9, 1974 Miami, Florida |
| Nationality | American |
| Fields | biochemistry |
| Institutions | Vanderbilt University |
| Alma mater | Washburn University |
| Known for | epinephrine |
| Notable awards | Nobel Prize in Physiology or Medicine in 1971 |
Earl Wilbur Sutherland Jr. (November 19, 1915 – March 9, 1974) was an American pharmacologist and biochemist. Sutherland was born in Burlingame, Kansas. He won a Nobel Prize in Physiology or Medicine in 1971 "for his discoveries concerning the mechanisms of the action of hormones," especially epinephrine, via second messengers (such as cyclic adenosine monophosphate, cyclic AMP).
He received his bachelor's degree in chemistry in 1937 from Washburn University, Topeka, Kansas and earned his medical degree in 1942 from Washington University School of Medicine in St. Louis. After serving as a doctor in World War II, he returned to Washington University as a researcher in the pharmacology laboratory of Nobel laureate Carl Ferdinand Cori. In 1953, he became director of the department of pharmacology at Case Western Reserve University (then Western Reserve University) in Cleveland, Ohio, where he discovered the role of cyclic AMP in mediating the action of certain hormones. In 1963, desiring to limit his duties to research, Sutherland moved to Vanderbilt University School of Medicine in Nashville where he was a professor of physiology until 1973. Vanderbilt is also home to a residential dormitory, Sutherland House, named in Sutherland's Honor. A plaque and photographic display commemorate his achievements. He was elected to the National Academy of Sciences in 1966, won the Albert Lasker Award for basic medical research in 1970, and received the National Medal of Science in 1973. At the time of his death in 1974, Sutherland was a distinguished professor of biochemistry at University of Miami Medical School.
[edit] References
- Shampo, M A; Kyle R A (Jun. 2000). "Earl Sutherland--Nobel Prize for Hormone Research". Mayo Clin. Proc. 75 (6): 552. ISSN 0025-6196. PMID 10852412.
- Raju, T N (Sep. 1999). "The Nobel chronicles. 1971: Earl Wilbur Sutherland, Jr. (1915-74)". Lancet 354 (9182): 961. ISSN 0140-6736. PMID 10489991.
- Butcher, R W; Robison G A (Mar. 1975). "An appreciation of Earl Sutherland". Metab. Clin. Exp. 24 (3): 237-40. ISSN 0026-0495. PMID 1092953.
- Ho, R J; Russell T, Asakawa T (Mar. 1975). "The last conversation with Dr. Earl W. Sutherland, Jr: the feedback regulation of cyclic nucleotides". Metab. Clin. Exp. 24 (3): 257-64. ISSN 0026-0495. PMID 165349.
- "Dr. Sutherland, AHA career investigator, dies in Miami" (May. 1974). Circ. Res. 34 (5): 743. ISSN 0009-7330. PMID 4597081.
- Oye, I (Nov. 1971). "[The Nobel Prize in Medicine to Earl W. Sutherland Jr]". Tidsskr. Nor. Laegeforen. 91 (31): 2270-1. ISSN 0029-2001. PMID 4332258.
- "[Nobel prize for Medicine and Physiology 1972]" (Nov. 1971). Münchener medizinische Wochenschrift (1950) 113 (45): Suppl 45:1. ISSN 0027-2973. PMID 4942165.
- Kampmeier, R H (Nov. 1971). "Cycl AMP--and the Nobel Prize". South. Med. J. 64 (11): 1413-4. ISSN 0038-4348. PMID 4331313.
- "[Nobel prize for medicine 1971]" (Oct. 1971). Dtsch. Med. Wochenschr. 96 (44): 1735. ISSN 0012-0472. PMID 4939258.
- "Nobel prize" (Oct. 1971). Br Med J 4 (5781): 188. ISSN 0007-1447. PMID 4329929.
- "1971 Nobel Prize for physiology and medicine" (1971). Triangle; the Sandoz journal of medical science 10 (4): 173-4. ISSN 0041-2597. PMID 4337412.
- Ishikawa, E (Apr. 1969). "[Profile of Professor Earl W. Sutherland Jr]". Nippon Rinsho 27 (4): 1301-4. ISSN 0047-1852. PMID 4896683.
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Categories: 1915 births | 1974 deaths | American physiologists | Case Western Reserve University faculty | Pharmacologists | Nobel laureates in Physiology or Medicine | National Medal of Science laureates | Vanderbilt University faculty | Washington University in St. Louis alumni | People from Osage County, Kansas
