'''Boston's sign''' is the spasmodic lowering of the upper Eyelid on downward rotation of the Eye, indicating exophthalmic Goiter.[Cline D; Hofstetter HW; Griffin JR. ''Dictionary of Visual Science''. 4th ed. Butterworth-Heinemann, Boston 1997. ISBN 0-7506-9895-0]
Similar to Von_Graefe's_sign, it is observed in people with Graves-Basedow_disease, a type of Hyperthyroidism. In this Disease, the Immune_system attacks the Thyroid gland and the soft tissues surrounding the Eyes. As a result, the eyes are often pushed forward in the eye sockets, a condition known as Exophthalmos.
==References==
==See also==
*Graves_orbitopathy
Category:Eponymous_medical_signs
Category:Ophthalmology
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