Dalrymple's sign

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Dalrymple's sign is a widened palpebral (eyelid) opening, or eyelid spasm, seen in thyrotoxicosis (as seen in Graves' disease, exophthalmic Goitre and other hyperthyroid conditions), causing abnormal wideness of the palpebral fissure. As a result of the retraction of the upper eyelid, the white of the sclera is visible at the upper margin of the cornea in direct outward stare.^[1] It is named after British ophthalmologist, John Dalrymple (1803–1852).

Other eye signs described within the symptomology of Graves' disease are Stellwag's sign (rare blinking), Rosenbach's sign (tremor of the eyelids), and Jelink's sign (hyperpigmentation of the eyelid).

Dalrymple sign is lid retraction in primary gaze.

[edit] References

[edit] See also

• Graves ophthalmopathy
• Graves orbitopathy

[edit] External links

• Dalrymple's sign

v • d • e Eponymous medical signs for endocrinology, nutrition, and metabolism Endocrine disease hypoglycemia Whipple's triad Graves' disease/goitre eyelid: Abadie's sign · Boston's sign · Dalrymple's sign · Stellwag's sign · lid lag (Von Graefe's sign, Griffith's sign) extraocular muscles: Möbius sign hypothyroidism Queen Anne's sign Nutrition disorders vitamin B12 deficiency Schilling test rickets Harrison's groove carbohydrate Benedict solution Metabolic disorders             hypocalcaemia Chvostek sign, Trousseau sign of latent tetany PKU Guthrie test Other Beutler test M: END anat/phys/devp/horm/cell noco(d)/cong/tumr, sysi/epon proc, drug (A10/H1/H3/H5) M: NUT cof, enz noco, nuvi, sysi/epon drug(A8/11/12) M: MET mt, a/u/y/n/h, r/g/c/p/i, f/s/l/o, m, e, t au/y/n/h, rgcp/i, f/s/l/o, m, epon meds(A16, C10),intm(a/u/y/n/h, r/g/c/p/i, f/s/o, e, t)

v • d • e Eponymous medical signs for eyes and ears Eyes Adnexa lacrimal: Schirmer's test eyelid: Abadie's sign · Boston's sign · Dalrymple's sign · Stellwag's sign Globe pupil: Argyll Robertson pupils · Adie pupil · Marcus Gunn pupil iris: Fleischer ring · Kayser-Fleischer ring · Brushfield spots · Lisch nodule conjunctiva: Bitot's spots retina: Hollenhorst plaque · Roth's spot other: Alexander's law · Hirschberg test · Siegrist streaks · Hudson-Stahli line Ears auditory: Rinne test · Weber test vestibular: Unterberger test M: EYE anat(g,a,p)/phys/devp/cell noco/cong/tumr, epon proc, drug(S1A/1E/1F/1L) M: EAR anat(e,p)/phys/devp noco/cong, epon proc, drug(S2)

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