Deploy SharePoint for access from the Internet
You can set up a team site so that your colleagues can access from the Internet via a browser. I have my own site which allows me to share files with people. I find it useful when I need to get a large powerpoint presentation to a partner, and it is bounced either at the partner gateway or ours. I think I've got about 100mb on my site and a bunch of either contributors or readers of the site - all secured and accessing anything I put up there. it's really useful if you're restricted in the size of messages you can send at work and don't want to burn anything to a CD.
If you've clicked the link above, you will have noticed that you've been given an access denied message, but you're actually looking at the Share Point site. I give the relevant permissions (Reader, Contributor etc.) to the SMTP address, and they get an email advising them of a password to let them in to the site.
You can sign up for a free trial here, and there is also a White Paper that you can download here to deploy SharePoint portal server on an Extranet...
It's much easier than breaking large files down into smaller chunks and sending them by mail bit by bit..
Update: @ 1820hrs UK time - link to create a site now working...